Abstract
BackgroundGranulomatosis with polyangiitis and myxomas are rare conditions previously described to co-exist. Cardiac masses are often presumed to be myxomas rather than lesions of granulomatosis with polyangiitis.Case presentationWe present a review of the symptoms for the two diagnoses along with the first verified case.ConclusionsTwo possible risk factors for developing myxomas (VEGF and IL-6) are explored and discussed.
Highlights
Granulomatosis with polyangiitis and myxomas are rare conditions previously described to co-exist
Granulomatosis with polyangiitis (GPA) is a small- to medium-sized vasculitis histopathological characterised with granulomas [1]
Previous literature suggests that patients with GPA that present with cardiac masses are often inflammatory lesions of GPA and not myxomas [4, 7–9]
Summary
Granulomatosis with polyangiitis and myxomas are rare conditions previously described to co-exist. The authors initially presumed this cardiac mass to be a myxoma; no histopathological examination was documented, and it was later considered to be a lesion of GPA [7]. One article presented histopathological verification of a GPA lesion in a patient that was first believed to be an atrial myxoma [9]. To our knowledge, no case report has described a patient with GPA and a confirmed myxoma.
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