Abstract
Rift Valley fever virus (RVFV) causes large outbreaks of acute febrile and often fatal illness among humans and domesticated animals in sub-saharan Africa and the Arabian Peninsula. The RVFV is of the genus Phlebovirus, within the family Bunyaviridae. Like all members of this large family, it contains a three-segmented RNA genome of negative/ ambisense polarity, packaged into viral nucleocapsid protein, and finally surrounded by a lipid bilayer containing two viral glycoproteins. RVFV epidemiology, molecular biology, and virulence mechanisms have raised considerable interest over the past years. In the present article, we provide an overview of the basic features of this significant pathogen, and of the latest developments in this highly active research field.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.