Rifampin-warfarin interaction in a transcatheter aortic valve replacement patient with septic knee arthritis

Abstract

Warfarin therapy is known to participate in numerous drug-drug interactions that may cause substantial fluctuations in anticoagulation status. Rifampin is a commonly used antibiotic that also possesses the capability to interact with a multitude of medications, including warfarin, due to its strong induction capabilities on the CYP450 system, including CYP2C9, CYP3A4, CYP1A2, and CYP2C19