Ridge Alterations following Immediate Implant Placement and the Treatment of Bone Defects with Bio‐Oss in an Animal Model

Abstract

Conflicting data exist on the outcome of placing Bio-Oss® (Geitslich Pharm AG, Wolhausen, Switzerland) into extraction sockets. It is therefore relevant to study whether the incorporation of Bio-Oss into extraction sockets would influence bone healing outcome at the extraction sites. The aim of this study was to assess peri-implant bone changes when implants were placed in fresh extraction sockets and the remaining defects were filled with Bio-Oss particles in a canine mandible model. Six mongrel dogs were used in the study. In one jaw quadrant of each animal, the fourth mandibular premolars were extracted with an elevation of the mucoperiosteal flap; implants were then placed in the fresh extraction sockets and the remaining defects were filled with Bio-Oss particles. After 4 months of healing, micro-computed tomography at the implant sites was performed. Osseointegration was calculated as the percent of implant surface in contact with bone. Additionally, bone height was measured in the peri-implant bone. Average osseointegration was 28.5% (ranged between 14.8 and 34.2%). The mean crestal bone loss was 4.7 ± 2.1 mm on the buccal aspect, 0.4 ± 0.5 mm on the mesial aspect, 0.4 ± 0.3 mm on the distal aspect, and 0.3 ± 0.4 mm on the lingual aspect. The findings from this study demonstrated that the placement of implants and Bio-Oss® particles into fresh extraction sockets resulted in significant buccal bone loss with low osseointegration.