Abstract

During November 2008–July 2009, we investigated the origin of unknown fever in Senegalese patients with a negative malaria test result, focusing on potential rickettsial infection. Using molecular tools, we found evidence for Rickettsia felis–associated illness in the initial days of infection in febrile Senegalese patients without malaria.

Highlights

  • During November 2008–July 2009, we investigated the origin of unknown fever in Senegalese patients with a negative malaria test result, focusing on potential rickettsial infection

  • R. felis infection is generally diagnosed on the basis of both serologic assays and bacterial DNA detection by PCR (2–4)

  • In Africa, human R. felis infections have been reported in Tunisia (5) but not in Senegal

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Summary

Target gene

16.66% (3/18) in April, 6.89% (2/29) in June, and 2.38% (1/42) in July. Seven patients lived in Dielmo, and 1 lived in in Ndiop. The overall incidence was 1.7% in Dielmo and 0.3% in Ndiop (7/391 vs 1/313; p = 0.06), and for children

Conclusions
Findings
Signs and symptoms
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