Abstract
Rickettsia africae is the agent of African tick-bite fever, a mild but common disease of local persons and tourists in Africa. The major vector of this spotted fever group rickettsia is most likely Amblyomma variegatum, the tropical bont tick, which has become widely distributed through the West Indies in the last 30 years. This report reviews all available information on R. africae in the West Indies.
Highlights
Rickettsia africae is the agent of African tick-bite fever, a mild but common disease of local persons and tourists in Africa
R. africae is widely distributed in Africa, and serosurveys have shown infections are extremely common in humans [1], reports of African tickbite fever (ATBF) in indigenous people are unexpectedly rare
In 2003, Kelly et al [22] found 41% of A. variegatum from Saint Kitts and Nevis were positive for DNA of R. africae in polymerase chain reaction (PCR) in which rOmpA primers were used for the spotted fever group (SFG) rickettsiae
Summary
Rickettsia africae is the agent of African tick-bite fever, a mild but common disease of local persons and tourists in Africa. Rickettsia africae is a recently described spotted fever group (SFG) rickettsia that is the agent of African tickbite fever (ATBF), a mild but common tickborne disease of local persons and tourists, in particular, in sub-Saharan Africa. In Africa, the tropical bont tick, Amblyomma variegatum, is commonly infected with R. africae and is likely the major vector of the organism [3].
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