Abstract

An electron-microscope study of the HeLa-cell cytoplasmic and nuclear 74-S ribosomes has been performed. These behave similarly when cations are removed by versene: both break up into 30-S and 50-S subunits. In the heavy part of the centrifugation gradient used to isolate the ribosomes it has been shown that 74-S ribosomes are associated in polysomes and a rough calculation has shown that it is not unreasonable to believe that as many as 40 ribosomal units or more could exist in some polysomes.

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