Abstract
The entire atomic structure of one of the most important cellular machines, the ribosome, has been elucidated by workers at the University of California, Santa Cruz, USA. The structure reveals the relationship between the 30S and 50S subunits, and the hollow between them, in which protein synthesis takes place (reported on-line at Sciencexpress, 29 March). Harry Noller and co-workers studied the ribosome of the thermophilic organism Thermus thermophilus, bound with mRNA and tRNA, and observed three tRNA binding sites in contact with the ribosome, providing an explanation for the conservation of tRNA structure during protein synthesis. MJD
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