Abstract
Rhythm disorders in PAH are rare. In practice, they pose a therapeutic management challenge. Right ventricular dysfunction associated with hypoxia influences the prescription of antiarrhythmics; some of them are even contraindicated. We report three cases of idiopathic PAH complicated by atrial flutter (2 cases) and atrial fibrillation (1 case). The patients experienced right heart failure after a stabilization phase with specific vasodilators (bosentan, sildenafil, iloprost). They were treated with oral amiodarone, alongside treatment for right heart failure. Potassium levels were normal. Beta-blockers were not prescribed due to severe right ventricular dysfunction with arterial hypotension. Unfortunately, two patients developed hyperthyroidism secondary to amiodarone. Through these observations, we will discuss the different therapeutic options in these situations, referencing the literature.
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