Abstract
We present a case of a 71 year-old woman with a late prosthetic valve infective endocarditis with negative blood cultures. The cultures of tissue were taken during valve replacement surgery. Molecular identification of the culture obtained from the cardiac valve was confirmed by PCR amplification. The sequences showed identity with the 16S rRNA gene sequences of Rhodococcus erythropolis. After surgery, she completed 6 weeks of levofloxacin and clarithromycin and was transferred to a rehabilitation facility. To our knowledge this is the first case of non-equi infective endocarditis of a prosthetic valve in an apparently normal host. Also it highlights the importance of molecular studies in the diagnosis of IE with negative blood cultures.
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