Rhodium‐Catalyzed Asymmetric Hydrogenation

Abstract

This chapter contains sections titled: Introduction Chiral Phosphorous Ligands Atropisomeric Biaryl Bisphosphine Ligands Chiral Bisphosphane Ligands Based on the Modification of DuPhos and BPE Chiral Bisphosphane Ligands Based on the Modification of DIOP Chiral Ferrocene-Based Bisphosphane Ligands P-Chiral Bisphosphane Ligands Other Bisphosphane Ligands Bisphosphinite, Bisphosphonite, and Bisphosphite Ligands Chelating Aminophosphine- and Amidophosphine-phosphoramidites Chiral Monophosphorous Ligands Applications of Chiral Phosphorous Ligands in Rhodium-Catalyzed Asymmetric Hydrogenation Hydrogenation of Olefins Hydrogenation of Dehydroamino Acid Derivatives Hydrogenation of Enamides Asymmetric Hydrogenation of β-(Acylamino)acrylates Asymmetric Hydrogenation of Enol Esters Asymmetric Hydrogenation of Unsaturated Acids and Esters Hydrogenation of Ketones Hydrogenation of Functionalized Ketones Hydrogenation of Unfunctionalized Ketones Asymmetric Hydrogenation of Imines Acyclic N-Alkylimines C=N–X Substrates Conclusion References