Abstract
Cardiovascular diseases, also known as circulatory diseases, are diseases of the heart and blood vessels, and its etiology is hyperlipidemia, thick blood, atherosclerosis, and hypertension. Due to its high prevalence, disability, and mortality, it seriously threatens human health. According to reports, the incidence of cardiovascular disease is still on the rise. Rhodiola rosea is a kind of traditional Chinese medicine, which has the effects of antimyocardial ischemia-reperfusion injury, lowering blood fat, antithrombosis, and antiarrhythmia. Rhodiola rosea has various chemical components, and different chemical elements have the same pharmacological effects and medicinal values for various cardiovascular diseases. This article reviews the research on the pharmacological effects of Rhodiola rosea on cardiovascular diseases and provides references for the clinical treatment of cardiovascular diseases.
Highlights
Cardiovascular disease (CVD) is the general term for heart and vascular diseases, mainly including ischemic heart disease, cerebrovascular disease, peripheral vascular disease, and rheumatic heart disease
As a worldwide plant adaptogen, Rhodiola rosea is widespread throughout the world
(2) Rhodiola has the function of multitarget and multipathway in the protection of MIRI; salidroside inhibits the expression of vascular endothelial contractile factor and promotes the expression of vascular endothelial relaxation factor by inhibiting the gene expression of hypoxia-inducible factor 1α (HIF-1α), ET-1, and NOS
Summary
Cardiovascular disease (CVD) is the general term for heart and vascular diseases, mainly including ischemic heart disease, cerebrovascular disease, peripheral vascular disease, and rheumatic heart disease. In Europe, CVD causes 49% of mortality, which is the most important cause of premature mortality and disability adjusted life years (“DALYS”) in Europe. CVD has various complex causes and forms of the disease, and it is difficult to treat, which accounts for the first cause of death in the world, about 41%. According to the Global Biodiversity Information Facility, 136 Rhodiola species are recorded. In China, there are 73 Rhodiola species [5]. As a worldwide plant adaptogen [6], Rhodiola rosea can improve cardiovascular and cerebrovascular system functions. The structure of different chemical components of Rhodiola rosea is different, and its pharmacological effects and medicinal value for various cardiovascular diseases are other. This article reviews the pharmacological effects of Rhodiola rosea and its active ingredients on cardiovascular diseases in the past ten years
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