Abstract
AbstractThe human corneal endothelium shows poor regenerative abilities. In cases of pseudophakic bullous keratopathy or Fuchs’ dystrophy, descemet striping automated keratoplasty brings considerable clinical benefits. However there are still allograft rejections and the shortage of donor corneas is a problem that still needs to be solved. The Rho/Rho kinase (ROCK) inhibitors may help establishing ex vivo endothelial cell cultures and may also give birth to new pharmacological treatments of corneal endothelial dysfunction.
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