Rhinovirus Type in Severe Bronchiolitis and the Development of Asthma

Abstract

E Bergroth, M Aakula, V Elenius. J Allergy Clin Immunol Pract. 2020;8(2):588–595.e4 Respiratory syncytial virus (RSV) and rhinovirus (RV)-induced bronchiolitis are associated with increased asthma risk in children. Whether virus types have different risks associated with later development of asthma is not known. RV-A and RV-C cause more severe respiratory illness than RV-B. Cadherin-related family member 3, a receptor for RV-C, and atopy are risk factors for development of early-onset asthma. The current study investigates whether RSV or RV types are differentially associated with use of asthma medications in the 4 years following severe bronchiolitis in infancy. Children less than 24 months of age, hospitalized for bronchiolitis over consecutive winter …