Rhinosinutis and Asthma in Children

Alessia Marseglia,Valeria Paganelli,Thomas Foiadelli,Amelia Licari,Ilaria Brambilla,Riccardo Castagnoli,Gian Marseglia

doi:10.3390/sinusitis3020003

Abstract

Rhinosinusitis and asthma are two comorbid conditions that lead to pathological and clinical diseases affecting the respiratory tract. They are connected by significant anatomical, epidemiological, pathophysiological, and clinical evidence, and also share therapeutic principles. The aim of this review is to provide an updated overview of the existing link between rhinosinusitis and asthma focusing on the pediatric age.

Highlights

Rhinosinusitis and asthma represent a major public health problem, because of their frequency and their impact on quality of life, school performance and economic burden [1]
chronic rhinosinusitis (CRS) is broadly classified into two major phenotypes, based on nasal endoscopic and computed tomography (CT) findings: CRS with nasal polyposis (CRSwNP) and CRS sine nasal polyposis (CRSsNP) [2]
The aim of this review is to provide an updated overview on the existing link between rhinosinusitis and asthma focusing on pediatric age

Summary

Introduction

Rhinosinusitis and asthma represent a major public health problem, because of their frequency and their impact on quality of life, school performance and economic burden [1]. European Position Paper on Rhinosinusitis and Nasal Polyps, pediatric rhinosinusitis is defined as an inflammation of the nose and the paranasal sinuses characterized by two or more symptoms. Pediatric severe chronic upper airway disease (P-SCUAD) is a novel term introduced to define difficult-to-treat cases, characterized by the persistence of upper airway inflammation and symptoms despite correct diagnosis and management [10]. These cases often show a negative impact on quality of life, social functioning, and school or work performance [11]. The aim of this review is to provide an updated overview on the existing link between rhinosinusitis and asthma focusing on pediatric age

Rhinosinusitis and Asthma in Children

Anatomical Evidence

Epidemiogical Evidence

Pathophysiological Mechanisms

Clinical and Therapeutic Management

Findings

Conclusions