Abstract
A 55-year-old diabetic female presented with persistent headache, bilateral nasal blockage, common cold and nasal discharge since 10 days. The patient also complained of bilateral nasal bleeding, anosmia and ptosis of the eye since the last five days. Clinical diagnosis of rhino-orbito-cerebral was confirmed by computed tomography (CT) scan of paranasal sinuses and brain. The diagnosis of fungal infection due to Rhizopus species was confirmed by Potassium hydroxide (KOH) examination, Hematoxylin and Eosin staining and Gomori's Methenamine Silver Nitrate staining on mucosal biopsy, followed by culture on Sabouraud's Dextrose agar. Surgical debridement was done and intravenous Amphotericin B was administered to the patient, who responded well to the treatment.
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