Abstract
BackgroundCoronavirus disease 2019 (COVID-19) is known to be associated with a myriad of viral, fungal, and bacterial co-infections. Rhino-orbital mucormycosis is a rare angio-invasive fungal infection which has shown a rising trend in the setting of COVID-19.Case presentationWe describe the imaging findings in 3 cases of rhino-orbital mucormycosis in patients with history of COVID-19. All cases had varying involvement of paranasal sinuses extending into the orbital compartment while case 3 had intracranial extension of infection.ConclusionsRhino-orbital mucormycosis can have aggressive necrosis of the involved paranasal sinuses and orbits with or without cerebral extension. Hence, the correct diagnosis is imperative as prompt antifungal drugs and surgical debridement can significantly reduce mortality and morbidity.
Highlights
BackgroundThe 2019 novel coronavirus disease (COVID-19) is an infectious viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1]
Coronavirus disease 2019 (COVID-19) is known to be associated with a myriad of viral, fungal, and bacterial co-infections
The 2019 novel coronavirus disease (COVID-19) is an infectious viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1]
Summary
The 2019 novel coronavirus disease (COVID-19) is an infectious viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1]. COVID-19 is known to cause respiratory symptoms primarily, ranging from mild to severe pneumonia [4] It can be associated with a broad-spectrum of bacterial and fungal co-infections [5]. Histopathological evaluation (HPE) of the nasal discharge revealed broad aseptate ribbon-like fungal hyphae on KOH wet mount [12]. CE-MRI of the paranasal sinuses and orbits revealed mucosal thickening and collection in the right maxillary sinus causing blockage of right osteomeatal unit (Fig. 3a). KOH mount of nasal discharge revealed broad aseptate fungal hyphae, later confirmed on culture showing broad ribbon-like hyphae with sporangium (Fig. 3d). CE-MRI of the paranasal sinuses, brain, and orbits revealed mucosal thickening and collection involving frontal, ethmoidal, sphenoidal, and left maxillary sinuses (Fig. 4a). Broad aseptate ribbon-like hyphae with sporangium is seen on the LPCB stain after 72 h of culture in SDA agar (Fig. 4d)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
