Abstract
Rheograms were obtained with a Ferranti-Shirley cone and plate viscometer at 20, 2 5, 30, and 35° for 13 pharmaceutical semisolids. As the temperature was raised, all the products studied showed a decrease in viscosity, thixotropy, and yield value. For many of the semisolids there appears to be a straight line relationship between thixotropic area and temperature. For ointments whose base is predominatety white ointment, the viscosity is reduced by a factor of 0.5 for every 5° rise in temperature. At 35° many of the products studied showed similar values for thixotropy and viscosity. Rheograms were obtained with a Ferranti-Shirley cone and plate viscometer at 20, 2 5, 30, and 35° for 13 pharmaceutical semisolids. As the temperature was raised, all the products studied showed a decrease in viscosity, thixotropy, and yield value. For many of the semisolids there appears to be a straight line relationship between thixotropic area and temperature. For ointments whose base is predominatety white ointment, the viscosity is reduced by a factor of 0.5 for every 5° rise in temperature. At 35° many of the products studied showed similar values for thixotropy and viscosity.
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