Abstract
The aim of this work is to investigate the effect of surface modification of superparamagnetic magnetite nanoparticles (sterically stabilized by sodium oleate) by the dextran biocompatible layer on the rheological behavior of water-based magnetic fluids. The flow curves were measured as a function of the magnetic field strength by means of rheometry. The measured viscosity is generally dependent on both the particle concentration and the geometrical factors such as the particle shape and thickness of the adsorbed layers. The rheological properties of the magnetic fluids studied show the effect of the magnetic field strength and the presence of the surfactant second layer (dextran) on their viscosity.
Highlights
Iron oxide nanoparticles are being developed for a wide range of biomedicine applications and diagnostics
The surface modification of magnetic nanoparticles with dextran enhances the stability of biocompatible magnetic fluids and leads to an increase of the viscosity of the magnetic fluids
A magnetic field can enhance the interaction among magnetic particles, and as a result, the viscosity increases under the external magnetic field
Summary
Iron oxide nanoparticles are being developed for a wide range of biomedicine applications and diagnostics A colloidal suspension of single magnetic domain particles is named a magnetic fluid (MF) [1]. Nanoparticles become composite objects made of a magnetic core surrounded by one or more nonmagnetic shells. Polysaccharides, due to their unique physicochemical properties and excellent biocompatibility, should be appropriate to prepare nanoparticles applicable for biomedical purposes. From a biomedical point of view, the adsorbed polymer layer should completely cover the particles and be as dense as possible in order to protect the iron oxide core against contact with blood proteins and phagocytosis-associated receptors [2]
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