Abstract

Abstract Nanofibers have been used with increasing success for drug delivery and various biomedical engineering applications. The mixture of 13% pullulan-aloe vera can be pumped with a minor effects on the flow behavior. The fiber is then characterized by SEM, shear viscosity, storage and loss moduli. The oscillatory shear data is employed. The mixture has a complex rheological properties that includes extreme shear-thinning as well as viscoelastic properties and yield stress. The rheology of the pullulan-aloe vera nanofber was characterized, the measurement method may influence the results, it is unclear how the behavior near walls influence the measurement method, Parallel-plate rheometer is used to measure rheological properties. The data and rheological parameters should facilitate a better understanding of the process-ability characteristics of the mixture. The cross model provides a simple way of quantifying the viscosity/shear rate profile for a shear thinning mixture. SEM images are carried out.

Highlights

  • Aloe vera is a therapeutic medicinal plant that has been used for many centuries to treat a wide range of ailments

  • We investigate the rheological properties of pullulanaloe vera nanofibers, which will provide insight into the material properties in a scaled-up manufacturing process

  • Scanning Electron Microscopy (SEM) images confirmed that pullulan- aloe vera nanofibers can be successfully developed as shown in Figure 2 and 3

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Summary

Introduction

Aloe vera is a therapeutic medicinal plant that has been used for many centuries to treat a wide range of ailments. There are over 250 species of the Aloe vera plant that have been studied. Studies have shown that the active ingredients in the aloe vera plant have demonstrated wound healing, antifungal, anti-inflammatory, anticancer, immunomodulatory and gastroprotective properties [2,3,4]. Despite the exceptional healing properties of the aloe vera plant, there are several limitations with keeping these active ingredients stable. Current techniques used to overcome these challenges have been focused on the usage of antioxidants and stabilizing agents. Such methods introduce other chemicals that would limit the scalability and purity of using non-toxic ingredients

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