Abstract
Biologically active pyrene based rhenium (I) complexes (1–2) were designed as fac-[Re(CO)3LCl], (where L = L1 (E)-N-(quinolin-8-ylmethylene)pyren-4-amine and L2 (E)-N-(pyridin-2-ylmethylene)pyren-4-amine) and structurally characterized by X-ray crystallography, which suggested a distorted octahedral geometry around the metal centre. The complexes were also characterised by various spectroscopic techniques. The binding of the rhenium complexes to CT-DNA was examined by UV–Vis spectroscopy, fluorescence quenching studies with ethidium bromide and viscosity measurements. Between both the complexes, 2 showed a greater binding ability to CT-DNA, as is evident from the numerical value of the binding constant, calculated using the Benesi-Hildebrand equation.
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