Rhabdomyolysis Induced Acute Kidney Injury in Hyperglycemic Hyperosmolar State Patient With New-Onset Diabetes: A Case Report.

Qasim Khurshid,Anas Mahmoud,Laila Khalid,Norina Usman,Neelam Neupane

doi:10.7759/cureus.9188

Abstract

The hyperglycemic hyperosmolar state (HHS) is a serious acute complication of type 2 diabetes mellitus that requires prompt recognition, diagnosis, and treatment. Reversible acute kidney injury is common in hyperglycemic states. However, hyperglycemic emergencies can contribute to the development of rhabdomyolysis, which can further aggravate acute kidney injury and can cause high morbidity and mortality. HHS can be the first clinical presentation of diabetes mellitus in some patients. Here, we present a case of HHS-related rhabdomyolysis and acute kidney injury, which was the first presentation of type 2 diabetes mellitus in this patient. Our case highlights the importance of a rare association between rhabdomyolysis and HHS in diabetic patients.

Highlights

Hyperglycemic hyperosmolar state (HHS) is a life-threatening acute metabolic complication of diabetes mellitus
The clinical features of rhabdomyolysis can vary from being asymptomatic to life-threatening acute renal failure requiring renal replacement therapy and a missed diagnosis can be associated with a high mortality rate
We describe a case of rhabdomyolysis associated with HHS and complicated with acute kidney injury in a newly diagnosed type 2 diabetes mellitus patient

Summary

Introduction

Hyperglycemic hyperosmolar state (HHS) is a life-threatening acute metabolic complication of diabetes mellitus. We describe a case of rhabdomyolysis associated with HHS and complicated with acute kidney injury in a newly diagnosed type 2 diabetes mellitus patient. This case may help clinicians to improve treatment and outcomes for such patients. Based on these laboratory findings, she was diagnosed with HHS, acute kidney injury, rhabdomyolysis, and pneumonia. She was followed up in outpatient after two weeks, and all lab investigations were within normal limits. The authors thank the patient for agreeing to participate and for providing a detailed medical history

Discussion

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Disclosures

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