Abstract
Purpose: The Highly Specialised Service (HSS) for McArdle disease and related disorders in the United Kingdom receives many referrals to investigate the cause of exercise-induced pain and rhabdomyolysis, a complex medical condition involving rapid breakdown of damaged skeletal muscle. An increasing number of these referrals are following unaccustomed exercise. Since January 2017 twenty two such patients have been assessed in clinic. A typical history reveals either a period of inactivity followed by an intense training session at the gym, often with a personal trainer, prior to an episode of rhabdomyolysis. The aim of this service evaluation is to highlight the need for caution in training individuals returning to exercise, particularly after a break from exercise of at least two months.
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