Abstract
The circular dichroism (CD) of in situ formed complexes of steroidal substituted secondary and tertiary alcohols with [Rh 2(OCOCF 3) 4] have been investigated. The applicability of the bulkiness rule, developed for unsubstituted secondary alcohols and connecting the sign of the E band at ca. 350 nm with the absolute stereochemistry of an alcohol, is extended to substituted secondary and tertiary alcohols. The rule works well for secondary and tertiary alcohols containing a double bond, alkoxy, ester or amide groups, halogen substituents as well as additional primary hydroxy groups in a molecule. The influence of other substituents present at the stereogenic center, e.g. a keto-, amino-, azido- or additional hydroxy groups, on CD is also described. It is demonstrated that alcohol molecules bind to the Rh-core at axial positions to form 1:2 adducts of the general formula [Rh 2(OCOCF 3) 4(alcohol) 2].
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
