Abstract
We introduce a model that describes rearrangement pathways of DNA recombination events. The recombination processes may happen in a succession, possibly with some recombination events performed simultaneously, but others in a prescribed order. These events are modeled by three rewriting rules applied on a set of formal linear and circular words. We define a partial order on these sets in such a way that two sets are related by this order when molecules represented by one are produced by recombination events from the other. We apply our model to experimental data obtained for DNA rearrangement of the actin I gene in O. trifallax ciliates, and we predict possible pathways of gene rearrangement compatible with the data.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.