Abstract

The study investigates the ability of Greek-speaking individuals diagnosed with mild Alzheimer's Disease (mAD) and Mild Cognitive Impairment (MCI) to produce verbs that vary with respect to their grammatical and lexical aspect. While grammatical aspect has been examined in aphasia, there are only a few studies dealing with this in neurodegenerative conditions and their findings are contradictory. Motivated by this, we further investigate aspect by examining not only grammatical but lexical aspect as well and how their semantic and temporal features affect mAD and MCI individuals' performance. Thus, the major innovation of the study is that it examines aspect not only as a functional feature but also as a lexical variable, something addressed for the first time in the literature. We also address whether grammatical aspect interacts with lexical aspect and with time reference. Finally, by looking at Greek, we further contribute to cross-linguistic perspective of aspect investigation. 11 MCI and 11 mAD individuals participated in a picture naming task, targeting the investigation of lexical aspect, and a sentence completion task, targeting the investigation of grammatical aspect and its interaction with lexical aspect and time reference. Both groups of participants were found to be impaired in both tasks when compared to healthy controls. In the naming task, both group and lexical aspect were significant predictors for participants' performance. Specifically, more impaired performance was found in states (believe), achievements (break), and semelfactives (hit) compared to activities (run) and accomplishments (build) for both AD and MCI participants. In the sentence completion task, apart from group, neither grammatical or lexical aspect nor tense were significant predictors for participants' performance. While results indicate that both grammatical and lexical aspect are impaired in AD and MCI, a closer look suggests a dissociation regarding the temporal feature of duration. Specifically, as grammatical feature, duration does not appear to affect participants' choice between perfective and imperfective aspect. As a lexical variable, on the other hand, and as part of the lexical representation of a verb, duration (together with internal structure) appears to play a role in verb naming. Finally, the lack of interaction between lexical and grammatical aspect also indicates that these two subsystems can be affected differentially.

Highlights

  • Alzheimer’s disease (AD) is a chronic neurodegenerative disease and the most common type of dementia (Visser et al, 1999), characterized by progressive cognitive dysfunction

  • Regarding mild Alzheimer’s Disease (mAD), participants were included in the study if they fulfilled the following criteria: (1) a diagnosis of AD according to the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer’s and Related Disorders Association (NINCDSADRDA), (2) Clinical Dementia Rating (CDR) score = 1, (3) impairment in at least two cognitive domains, and (4) general cognitive function (MoCA score from 14 to 20)

  • Concerning Mild Cognitive Impairment (MCI), participants who were tested on List 1 performed significantly better on the picture-naming task compared to those who were tested on List 2 (U = 27,570, p < 0.01, r = 0.20), while in the sentence-completion task participants who were tested on List 2 performed better compared to those who tested on List 1 (U = 36,075, p = 0.013, r = 0.10)

Read more

Summary

Introduction

Alzheimer’s disease (AD) is a chronic neurodegenerative disease and the most common type of dementia (Visser et al, 1999), characterized by progressive cognitive dysfunction. Dysfunction in other cognitive domains, such as executive functions, attention and visuospatial skills, is observed. The term Mild Cognitive Impairment (MCI), refers to the clinical stage between normal aging and dementia. Individuals diagnosed with MCI suffer from loss of cognitive and functional abilities, yet they do not meet the criteria to be diagnosed with dementia (Petersen et al, 2001). Patients who demonstrate impairment in multiple cognitive domains, with or without degraded memory, including language, are more likely to develop dementia (Petersen et al, 2001; Petersen, 2003; Alexopoulos et al, 2006)

Objectives
Methods
Results
Conclusion
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call