Revised clinical pathway for the management of peritoneal metastases from colorectal cancer using NCCN 2017 guidelines

Abstract

In 2017, the National Comprehensive Cancer Network revised their guidelines for the treatment of peritoneal metastases from colorectal cancer. The panel now believes that complete cytoreduction and/or intraperitoneal chemotherapy can be considered for selected patients with limited peritoneal metastases for whom R0 resection can be achieved. This manuscript describes the intraperitoneal chemotherapy treatments that have been shown to be safe. It suggests that intraoperative, early postoperative and long-term combined intravenous and intraperitoneal chemotherapy can be utilized as a treatment package that is within the current National Comprehensive Cancer Network guidelines. Multiple time points for intraperitoneal chemotherapy treatment need to be exploited.