Abstract

The Outbreak of coronavirus disease 2019 (COVID-19) has become a global pandemic since December 2019. In order to combat the COVID-19, researchers have carried out many related experiments, including the pathogenesis of virus, to understand the structure and mechanism of the novel coronavirus. In addition, they have conducted in vitro and clinical trials for drug development. In this paper, the possible drug targets are discussed from the perspective of inhibiting virus entry into cells and inhibiting virus replication. In addition, the structure of the virus and its mechanism of entry into host cells are reviewed. Through this review, drug researchers can have a comprehensive understanding of the potential targets being investigated.

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