Review on Virosomes: As a Drug Delivery Carriers

Abstract

Since the last era, some revolutionary advances in drug delivery technologies have been observed in the realization of targeted drug delivery or targeted drug action at the site. The prospects for the use of biological molecules nanoparticles such as virosomes as drugs are motivating research and development areas that show the targeted fusion effects with the targeted fusion effects by target cells. Virosomes are biocompatible, biodegradable, non-toxic and non-autoimmunogeneous viral species and are new carriers and drug delivery systems for vaccines and cell delivery of active macromolecules. Virosomes are biomimetic nanoparticle drug delivery systems that contain active macromolecules in a virus coat made of lipoid membranes. The administration of virosomes takes place through various methods such as the intramuscular (IM), intravenous (IV), intravascular, subcutaneous (SC), oral and inhalation routes. The research paper focuses on the structure, components, types and formulations of virosomes, the mechanism of action and applications of viral genes, and available commercial formulations.