Abstract
Standardization in Ayurvedic formulations ensures the establishment of standards for the quality and purity of raw materials, quality control during the drug manufacturing process, production of a good quality finished product, storage and distribution to maintain the quality of the final product. It is an essential tool for establishing quality control methods for Ayurvedic drugs. In Ayurveda, standardization has been well defined and documented in the classical and contemporary texts. Still, these have been written with an individualistic intent and not for industrial or commercial purposes. Careful contemplation of the classical literature of Ayurveda was done, the current guidelines of WHO on standardization of herbal drugs, latest researches on the same via the internet were explored and examined in the purview of the newest standardization procedures. In this article, an attempt has been made to bring to light the classical references related to standardization, the milestones in this on-going pursuit have been exhibited, with the use of the latest scientific methods being incorporated for a standardized Ayurvedic drug. It can be concluded from the review that standardization in Ayurveda is an on-going process where one needs to be strictly vigilant about the new scientific methods to study the fine chemical procedures and the intermediate compounds formed, but at the same time be aware of the classical. Ayurvedic methods concepts of the procedure. Asava-arista's medicinal characteristics of Ayurvedic classical dosage forms, liquid dosage forms based on self-generated alcohol with faster absorption, long shelf life, and increased market conformity have led to a continuous rise in demand. New fermentation methods and packaging innovations tend to have been embraced by many Ayurvedic processing units. The importance of standardization of such goods is underlined by these advances in manufacturing, distribution and storage. Therefore, it is of concern to examine the latest manufacturing situation and the standardization of the dosage type regarding the procedure and the consistency and effectiveness of the finished product. In addition to the effort to include criteria of consistency and standardization, the study consists of an overview and deliberates on the importance of improvements made to the conventional preparation processes, ingredients and material used in the process and the potential impact on its efficacy.
Highlights
In addition to the effort to include criteria of consistency and standardization, the study consists of an overview and deliberates on the importance of improvements made to the conventional preparation processes, ingredients and material used in the process and the potential impact on its efficacy
Ayurvedic medicine system is advantageous to humanity, but there is still a lack of appropriate standardization techniques for determining its consistency, quantity and effectiveness
While much research has been attempted in recent years, there is still inadequate knowledge on herbal medicine phytochemistry and metabolomics, which has developed a major challenge in standardization methods [2]
Summary
Ayurvedic medicine system is advantageous to humanity, but there is still a lack of appropriate standardization techniques for determining its consistency, quantity and effectiveness. As per WHO guidelines, chromatographic methods are precise to standardize and admeasure the main biomarker molecules through nuclear drugs and formulations from poly-herbal. Thanks to thorough studies on the pharmacological impact on human health care, herbal remedies have steadily acquired significant acceptance and renown. While much research has been attempted in recent years, there is still inadequate knowledge on herbal medicine phytochemistry and metabolomics, which has developed a major challenge in standardization methods [2]. The proper protection and effectiveness standards for human quality of life should be practised by herbal remedies or phytomedicine [3]. The quality management and standardization protocols of herbal drugs have required a system. For the authentication of herbal/polyherbal Ayurvedic formulations, standardization protocols using non-conventional analytical practices are required. Preliminary analysis of biologically susceptible marker agents is currently getting much successful in herbal medication verification and helps to decrease adulteration [6,7]
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