Abstract

• Review on 345 Pregnane Glycosides and their biological activities. • The pregnane glycosides are classified into two major types based on linkages. • Pregnane glycosides have antitumor activity in recent years. Pregnane glycosides are exist in Asclepiadaceae , Apocynaceae , Malpighiaceae , Ranunculaceae and Zygophyllaceae . This is a class of substances with steroids as the mother nucleus and containing a glyosidic bond structure. Modern pharmacology has shown that these compounds are a class of compounds with different structures and multiple biological activities. It has a good development prospect in anti-cancer and anti-tumor directions. This article reviews the chemical structures and biological activities of 345 compounds from 1984 to 2019.

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