Review on methods, applications and role of gold nano particles in cancer therapy

Abstract

Conventional drug delivery is replaced by targeted drug delivery to reduce toxicity, dose, to improve therapeutic efficiency and to provide better treatment for the patient. Nanotechnology has taken targeted drug delivery forward in recent years. Gold nanoparticles [GNPs] are one of the nano particles which are capable of treating different cancers with low toxic effects and high bioavailability. Shapes of gold nano particles plays an important role in toxicity level and differs from each other. Methods of preparing depends on the required shape of GNPs which includes in the production of nano rods, spheres, clusters, shells etc. One of the main method of GNPs synthesis is done by using sodium tetrachloroaurate (III) dihydrate and other methods include template method.. The property of easily penetrating into tumour cells has gained importance for GNPs. GNPs has wide range of applications in biomedical field which include detection of tumour, where GNPs mimic the natural pathway of macromolecules by using electrostatic forces, imaging by using transmission electronic microscopy and as bio labels.