Abstract

In this review article, an attempt was made to present an overview of diabetes mellitus. Diabetes mellitus (DM) is a group of insulin resistance syndrome characterized by a high blood sugar level over a prolonged period of time. Diabetes is not a contagious disease. We can say Insulin dependent disorder. Nowadays, Diabetes Mellitus detect in many more peoples all over the World. In this report, we all know about Diabetes Mellitus. In that, we include its classification, sign & symptoms, etiology, pathogenesis, diagnosis, treatment etc. It’s had Four types, namely type 1, type 2, gestational Diabetes Mellitus & Other specific types such as, lada, mody. Fatigue Polyphagia, Polydipsia, polyuria, vomiting, dehydration etc., are common signs & symptoms are observed in Diabetes Mellitus. Diabetes Mellitus is mainly caused by the destruction of beta cells in the pancreas. Its cause’s autoimmune disorders such as Addison’s Disease, Hashimoto’s Thyroiditis & Graves’ disease. Some genetic factors, prior family history, environmental factors, autoimmune destruction, high insulin resistance these factors increase the risk of the development of diabetes mellitus. Most of the diabetic patients are older adults. Blood Glucose tests are used to detect diabetes mellitus. Insulin therapy is helpful to prevent or treat diabetes mellitus. For some patients, we used Islet replacement therapy and stem cell therapy used. In diabetes mellitus treatment, some drugs are used, such as miglitol, metformin, nateglinide, pioglitazone, glipizide, dapagliflozin, colestimide, bromocriptine etc. it's known as anti-diabetic drugs. Diabetics patients are more fastly rise in World.

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