Abstract
The aim of the study of colon cancer is to introduce the basic information of cancer cell and the basic information of colon cancer. The research on colon cancer gave the information about hallmarks of cancer cell. exaggerated continuous proliferation, resistance to cell death as well as tumor suppressors, angiogenesis, spreading and metastasis and replicative immortality, the symptoms of colon cancer: Frequent bowel dysfunction (Diarrhea-constipation), Abdominal pain, nausea & vomiting, Pain during defecation, and Bloating, the types of colon cancer: Familial Adenomatous Polyposis (FAP) and Lynch syndrome, nonpolyposis Colorectal Cancer, and the treatment of colon cancer: Treatment strategies differ according to the stage and development of the tumor. Surgery and adjuvant chemo are the two common methods in stages 2 and 3 of the disease. Palliative care is most common in patients at stage 4 to improve quality of life. The information which extracted from papers from other researchers formed the research of colon cancer.
Highlights
Introduction of cancerCancer is a disease caused by uncontrolled cell division
Uncontrolled cell division is caused by the DNA damage, which dysfunction of tumor suppressors and oncogenes
Cancer cells are mainly governed by six hallmarks: exaggerated continuous proliferation, resistance to cell death as well as tumor suppressors, angiogenesis, spreading and metastasis, and replicative immortality. (Hanahan and Weinberg 2000)
Summary
Cancer is a disease caused by uncontrolled cell division (proliferation). Uncontrolled cell division is caused by the DNA damage, which (causes DNA mutations that can lead to) dysfunction of tumor suppressors and oncogenes. Cancer cells are mainly governed by six hallmarks: exaggerated continuous proliferation, resistance to cell death as well as tumor suppressors, angiogenesis, spreading and metastasis, and replicative immortality.
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