Abstract
Clinical trials are crucial to the practise of evidence-based medicine and health care reform, as demonstrated by the recent federal funding focus on comparative effectiveness research. Clinical trials have an impact on society as a whole by raising the quality of healthcare offered, in addition to having an impact on the individual patient by creating a wider range of effective therapies. Clinical trials may, however, also expose participants to unforeseen hazards, and skewed knowledge drawn from problematic clinical studies may unintentionally damage patients. A well-designed clinical trial's execution may seem simple, but it is based on meticulous procedures and oversight that adhere to fundamental ethical norms. I give an overview of the moral principles in this project.
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