Abstract
Human chorionic gonadotropin (HCG) has been amongst of essential part of medical diagnostics in gynaecology and oncology since its discovery. Application of gold nanoparticles in detecting HCG is due to gold nanoparticles possess extraordinary optical and physical properties, making them invaluable in various prominent aspects, including its synthesis, stabilization, and functionalization as a sensor. In addition, microfluidic analytical device, a platform for point-of-care testing and numerous applications in various field, can be applied for detection of HCG using diverse types of detection methods. From the literatures, combination of gold nanoparticles and microfluidic analytical device can be assembled to obtain a rapid, simple and user-friendly analytical site for detection of HCG.
Highlights
Home pregnancy testing dates back in 1350 BC during the era of Ancient Egypt, where wheat and barley seeds used to determine whether a woman was said to be pregnant or vice versa
After centuries passed and science modernized the world, home pregnancy testing focused on detection of human chorionic gonadotropin (HCG), the hormone secreted after successful implantation of zygote onto endometrium wall
HCG plays an important role in enrichment of endometrium wall for development of zygote
Summary
Home pregnancy testing dates back in 1350 BC during the era of Ancient Egypt, where wheat and barley seeds used to determine whether a woman was said to be pregnant or vice versa. ΜPAD was sought out for fulfilling the basis of rapid and simple analysis; cheap, simple, adaptable and disposable In this review, both materials will be united in order to develop an assay for a frequently mentioned hormone, HCG. Highlighting the aspect of synthesis of AuNP, a pioneering protocol that was reported back in 1951 mentioned ten different methods to synthesize AuNP [2]. AuNP synthesized were described to be spherical, measured at 10 – 13 nm in size, and spread onto onedimensional monolayer [3]. Comparing both researches, the former research produced citrate-capped colloidal gold, measured in 20 nm in size with 1.5 nm deviations. MJoSHT 2020, Volume 5, Issue 1, eISSN: 2601-0003 study shown an exemplary improvement in synthesizing AuNPs using citrate reduction method with addition of reductant and fine-tuning the molar ratio used
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
