Review of Proliposomal Gel for Transdermal drug delivery system

Abstract

Proliposomes are an innovative kind of carrier-mediated drug delivery that offers numerous advantages over traditional liposomes. The conventional liposomes are susceptible to oxidation or hydrolysis, as well as sedimentation, aggregation, or fusion with other substances. While, proliposomes are far more stable than liposomes, making them better suited for the delivery of pharmaceuticals. They are a dry, free-flowing, granular substance that, when it comes in touch with water or a biological fluid inside the body, instantly transforms into a liposomal dispersion. Future systems for delivering medications could be proliposomes. They have achieved a considerable improvement in resolving the stability, bioavailability, and solubility of poorly soluble medicines difficulties associated with liposomes with their non-invasive drug administration into or across the skin. They are a better alternative to the liposomal vesicular system because of their increased physical and chemical stability and potential for scalability for commercial viability. Because they are in dry powder form, they can be manufactured into unit dose forms like tablets, capsules, and beads, among other things. Because of all these advantages, proliposomes have been used for a variety of medical applications.