Abstract
Jaundice is the most common finding during neonatal period. It is observed during the 1st week of life in approximately 60% of term infant and 80% of preterm infants. Level of serum bilirubin is not raised that much so as to cause fatal brain damage. It is the most common disease during neonatal period occurring mostly due to increased hemolysis, decreased hepatic clearance, enterohepatic circulation, immaturity, blood group incompatibility and infections. Its management includes 1] Phototherepy 2] Exchange transfusion are two major effective therapeutic modalities available today. Additional options include Pharmacotherapy in the form of phenobarbital and high dose intravenous immunoglobulin.
Highlights
Jaundice is an important problem in the 1st week of life
60% of terms new born become visibly jaundiced in the 1st week of life
5-10% of them have clinically significant jaundice mandating the use of phototherapy or other therapeutic options
Summary
Jaundice is an important problem in the 1st week of life. It is the yellow discolouration of the skin and sclera due to raised serum bilirubin. Under normal circumstance the level of indirect bilirubin in umbilical cord serum is 1-3 mg/dl and rises at a rate of
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