Abstract
In the last decade, interest has been renewed in approaches for the assessment of the bioaccumulation potential of chemicals, principally driven by the need to evaluate large numbers of chemicals as part of new chemical legislation, while reducing vertebrate test organism use called for in animal welfare legislation. This renewed interest has inspired research activities and advances in bioaccumulation science for neutral organic chemicals in aquatic environments. In January 2013, ILSI Health and Environmental Sciences Institute convened experts to identify the state of the science and existing shortcomings in terrestrial bioaccumulation assessment of neutral organic chemicals. Potential modifications to existing laboratory methods were identified, including areas in which new laboratory approaches or test methods could be developed to address terrestrial bioaccumulation. The utility of "non-ecotoxicity" data (e.g., mammalian laboratory data) was also discussed. The highlights of the workshop discussions are presented along with potential modifications in laboratory approaches and new test guidelines that could be used for assessing the bioaccumulation of chemicals in terrestrial organisms.
Highlights
Interest has been renewed in approaches for the assessment of the bioaccumulation potential of chemicals, principally driven by the need to evaluate large numbers of chemicals as part of new chemical legislation, (e.g., Environment Canada DSL [Environment Canada 2003], REACH [ECHA 2007])
The goals of this manuscript were to 1) discuss existing knowledge and data gaps pertinent to the laboratory assessment of terrestrial bioaccumulation; 2) identify potential improvements or additional parameters that could be incorporated into existing test guidelines to facilitate assessments of potential bioaccumulation in terrestrial organisms; and 3) identify new nonvertebrate bioaccumulation test methods to fill identified data gaps
Renewed interest in bioaccumulation in terrestrial organisms and food chains is being driven by a perceived inadequacy of aquatic assessments and the need to evaluate large numbers of chemicals as part of recent chemical legislation
Summary
Interest has been renewed in approaches for the assessment of the bioaccumulation potential of chemicals, principally driven by the need to evaluate large numbers of chemicals as part of new chemical legislation, (e.g., Environment Canada DSL [Environment Canada 2003], REACH [ECHA 2007]). If the suggested considerations for bioaccumulation were addressed (Supplemental Data Table 2), a study following these guidelines could provide data useful in determining a BAF value based on the ratio of test chemical in the plant tissue relative to the growth substrate at the time of sampling.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Integrated environmental assessment and management
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
