Abstract
Acute ischemic stroke is a leading cause of death and disability. Treatment efficacy is highly time-dependent. Approximately 20% of acute ischaemic stroke occurs in the posterior circulation. Clinical presentation of posterior circulation stroke is subtle. Diagnosis is often delayed and frequently missed. CT perfusion has improved diagnostic accuracy and been integral to guiding acute therapy in patients with anterior circulation stroke. There are limited studies assessing the role of CT perfusion in posterior circulation stroke. This review provides a reference for interpretation of CT perfusion and summarises current evidence relating to applications in acute posterior circulation stroke.
Highlights
Stroke is globally one of the leading causes of death and disability
Studies established the role of thrombolysis and endovascular thrombectomy within 4.5 h and 6 h from symptom onset, respectively, of an eligible ischaemic stroke
Studies have reported that up to 90% of posterior circulation acute ischaemic strokes (PCS) do not meet the criteria for TIA at first medical contact[12]
Summary
Stroke is globally one of the leading causes of death and disability. Acute treatment for ischaemic stroke is highly effective but partly time-dependent. Treatment depends upon expedient clinical appraisal of medical imaging. Current guidelines use a specific time window from stroke onset to determine eligibility for reperfusion therapy[1,2]. Due to this limited time frame, only a minority of potentially eligible strokes receive www.vpjournal.net These studies have expanded the number of patients eligible for acute reperfusion therapies
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