Abstract
Fomitopsis pinicola is a well-known medicinal mushroom commonly used in Chinese traditional medicine and Korean folk medicine for many years, and it is believed as a non-toxic medicinal mushroom that has many clinical effects on the human body with no sub-acute toxic impacts. In recent years, the use of medicinal mushrooms is enhanced greatly. Several different principal chemical constituents are present in the fruiting bodies of F.pinicola . These principal compounds were extracted from fruiting bodies of F.pinicola , have medicinal qualities and give different pharmacological impacts in the human body. The motive of the current review paper was to intricate the principal chemical constituents that are extracted from F.pinicola fruiting bodies and demonstrate the pharmacological effects of these extracts. F.pinicola extracts have no toxic side effects on vital organs such as liver, kidney, heart, spleen, pancreas, lungs and brain. The present study describes that both low molecular weight and high molecular weight compounds that are present in the fruiting bodies of F.pinicola . This included many useful enzymes, steroids, triterpenes and triterpenes derivatives, anti-tumor active constituents, and health beneficial nutritious compounds. These principal compounds showed important medicinal effects on the human body by providing a shield effect to the internal organs against diseases and also heal the damaged tissues and organs. The pharmacological effects of F.pinicola active constituents include anti-tumor, anti-diabetic, anti-hyperlipidemic by controlling obesity, anti-oxidant effect, anti-microbial, anti-inflammatory and also showed an industrial waste treatment effect. Keywords: Fomitopsis pinicola, Chinese traditional medicine, chemical constituents, pharmacological effects, waste treatment. DOI : 10.7176/JNSR/10-2-07 Publication date: January 31 st 2020
Highlights
Fomitopsis pinicola karst was recognized in 1881 as a brown rot basidiomycete species present typically on coniferous and seldom on deciduous trees, widely distributed throughout Asia, Europe, and America
Mushrooms are the best source of medicine and nutrition as its extracts give biological effects in the human body to treat many diseases
The purpose of this study was to provide a brief knowledge about the chemicals that are extracted from F.pinicola fruiting bodies and their pharmacological effects on the human body
Summary
Fomitopsis pinicola karst was recognized in 1881 as a brown rot basidiomycete species present typically on coniferous and seldom on deciduous trees, widely distributed throughout Asia, Europe, and America. Many chemical extracts are prepared from fruiting bodies of F.pinicola that contain many useful enzymes like endoglucanase, xylanase, laccase, cellobiohydrolase, β-1,4-glucosidase, nutritional components such as chitan and chitosan, triterpenes, triterpene derivatives including triterpenic alcohol, lanostane triterpenoids, triterpene glycosides, steroids, biological active polysaccharides {Endopolysaccharides and Exopolysaccharides} and antitumor active constituents etc. Several extracts are prepared from their fruiting bodies that showed physiological effects Its principle constituents such as triterpenes and its derivatives, enzymes, steroids, heteroglactan, glycosides, polysaccharides, chitan, and chitosan, giving physiological effect in the human body to cure a disease or used as a nutritional mushroom. The physiological effects include anti-tumor, anti-diabetic, anti-obesity, anti-oxidant, anti-inflammatory, antimicrobial and COX-1 and COX-2 inhibition, etc
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