Abstract
Background The ‘cohort multiple randomised controlled trial ’ (cmRCT) is an innovative approach to the design and conduct of RCTs which compare the effectiveness of interventions to usual care (Relton et al, 2010). The design utilises a large long term observational cohort of people with the condition of interest, regularly measuring the outcomes of the whole cohort. The cohort in the cmRCT design allows multiple trial populations to be quickly identified and recruited and interventions tested against usual care. Information consent processes are similar to those in routine healthcare.
Highlights
The ‘cohort multiple randomised controlled trial’ is an innovative approach to the design and conduct of RCTs which compare the effectiveness of interventions to usual care (Relton et al, 2010)
The cohort in the cmRCT design allows multiple trial populations to be quickly identified and recruited and interventions tested against usual care
16 studies implementing the cmRCT design were identified with a total of 18 ongoing or completed trials were embedded within these cohorts
Summary
The ‘cohort multiple randomised controlled trial’ (cmRCT) is an innovative approach to the design and conduct of RCTs which compare the effectiveness of interventions to usual care (Relton et al, 2010). The design utilises a large long term observational cohort of people with the condition of interest, regularly measuring the outcomes of the whole cohort. The cohort in the cmRCT design allows multiple trial populations to be quickly identified and recruited and interventions tested against usual care. Information consent processes are similar to those in routine healthcare
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
