Abstract
This retrospective review assessed adjuvant IVIG treatment in six patients with refractory Pyoderma Gangrenosum. All patients reported decreased ulcer size or depth, with one achieving complete healing. Most had a reduction in pain, and an increase in pain coincided with disease flares. IVIG was well-tolerated, though two patients required hospitalisation for infection management. Results suggest IVIG is a safe and effective option for refractory PG, with pain reduction potentially serving as a marker for treatment response, though recurrence remains a concern.
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