Abstract
Chemotherapy is one of the main treatment methods in malignant tumor. Tumor multidrug resistance (MDR) is one of the important reasons for the failure of chemotherapy. It makes some progress in reversing tumor MDR, such as chemical drug, traditional Chinese medicine, immunotherapy, gene therapy, nanoparticles drug system and so on. But it takes more effort to develop medicine of less adverse reactions, better pharmacodynamic and application to clinic widely. Key words: Neoplasms; Drug therapy; Multidrug resistance-associated proteins
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