Abstract

Preview Results of recently completed and ongoing trials may change the thinking on how to treat atherosclerosis. For example, even faithful adherence to the American Heart Association step 2 diet may not halt progression of established coronary artery disease. Also, current goals of lipid-lowering therapy may be inadequate to reverse coronary artery narrowings. Dr Kahn describes studies that have used more drastic measures to control hyperlipidemia, the effects of these measures on coronary atherosclerosis, and clinical application of results.

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