Abstract
The use of lithium carbonate in man has historically been associated with three types of cardiovascular side effects: T-wave changes in the electrocardiogram,1 , 2 ventricular arrhythmias3 , 4 and myocarditis.4 , 5 Recently, Wellens et al. showed that chronic lithium therapy also can cause reversible symptomatic sinus-node abnormalities.6 A similar phenomenon was observed in the following patient.Case ReportA 64-year-old secretary was admitted to Cleveland Metropolitan General Hospital in August, 1975, for evaluation of sinus bradycardia. Since 1968, she had been on lithium carbonate therapy for a manic-depressive psychosis.One month before admission, she began to have difficulty keeping her balance while ascending and . . .
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