Abstract
Four patients with Addison's disease are described in whom reduced thyroid function was demonstrated at the time of diagnosis of adrenocortical insufficiency. Replacement therapy consisting of physiological doses of adrenal steroids alone led to complete recovery of thyroid function in these patients, suggesting that hypothyroidism occurring in association with adrenal insufficiency may be reversible. The reason for the improvement in thyroid function after treatment with adrenal steroids is unknown.
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