Abstract
A particulate fraction from human leukaemic blood cells contains an RNAase-sensitive endogenous DNA polymerase system. This DNA polymerase was purified and it transcribes heteropolymeric regions of AMV 70S RNA. These and other template characteristics are similar to those of RNA tumour virus reverse transcriptase and appear to distinguish this leukaemic DNA polymerase from other normal cellular DNA polymerases.
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