Abstract

Recent contributions by Alvarez 1 and Keeton 2 have presented interesting and valuable evidence as to the cause of nausea. Both find the bowel to be an important factor in nausea production. For a number of years, Alvarez has considered it probable that it is brought about by reverse peristalsis, particularly in the bowel. 3 Clinical evidence has not been abundant, because of evident difficulties in human experimentation. A case recently observed, however, demonstrates very definitely the association of reverse peristalsis and nausea. REPORT OF CASE Mrs. E. M., aged 61, referred to me by Dr. H. M. Greene, July 27. 1925, gave a history of intermittent abdominal distress for several months up until two years ago. A diagnosis of peptic ulcer was made by the family physician, After treatment, she was comfortable until three weeks before I saw her, when pain in the epigastrium reappeared. At times, it

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