Abstract
Ethionine inhibition of elongation of Avena coleoptiles has been measured in water and in 3-indoleacetic acid. In the presence of 0.01 M 1-ethionine the inhibition amounts to about 70%. The application of adenosine triphosphate (ATP) effectively counteracts this inhibition; optimal ATP concentrations are between 2.5 and 5 × 10 −4 M. In the absence of ethionine ATP still exhibits a stimulatory effect on elongation. It is suggested that ethionine may exert its inhibiting effect on the protein synthesis necessary for elongation of the oat coleoptile by interference with ATP metabolism.
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